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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
7.88
Human Site:
S642
Identified Species:
14.44
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S642
I
E
P
P
K
V
S
S
Q
E
R
P
L
K
V
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S642
I
K
P
P
K
V
S
S
Q
E
R
P
L
K
V
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
P640
K
V
S
S
Q
E
R
P
L
K
V
P
S
E
L
Dog
Lupus familis
XP_537198
743
82483
S642
T
K
P
P
N
M
S
S
Q
E
R
R
L
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
P639
P
Q
V
S
Q
E
R
P
L
K
A
P
S
G
L
Rat
Rattus norvegicus
Q5M9F8
807
89107
W690
H
K
S
L
D
S
H
W
S
S
W
E
V
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
G1416
P
G
S
S
S
G
G
G
P
T
R
S
P
K
F
Chicken
Gallus gallus
NP_001012613
698
77220
E619
R
K
P
V
Q
D
P
E
L
D
W
F
A
D
M
Frog
Xenopus laevis
Q561M0
827
91284
N736
T
R
P
A
S
D
Y
N
W
E
S
P
G
T
A
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
R664
T
S
L
S
S
E
P
R
P
K
S
T
I
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
Q606
S
E
L
D
I
K
V
Q
T
V
I
Q
R
S
E
Honey Bee
Apis mellifera
XP_001123124
613
70111
D537
M
S
D
I
S
E
L
D
I
K
N
S
K
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
W707
A
P
L
S
T
T
K
W
K
K
G
T
F
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
93.3
6.6
60
N.A.
6.6
0
N.A.
13.3
6.6
20
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
33.3
73.3
N.A.
33.3
20
N.A.
13.3
33.3
26.6
20
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
8
0
8
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
16
0
8
0
8
0
0
0
16
0
% D
% Glu:
0
16
0
0
0
31
0
8
0
31
0
8
0
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
8
0
0
0
8
8
8
0
0
8
0
8
8
8
% G
% His:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
16
0
0
8
8
0
0
0
8
0
8
0
8
0
8
% I
% Lys:
8
31
0
0
16
8
8
0
8
39
0
0
8
31
0
% K
% Leu:
0
0
24
8
0
0
8
0
24
0
0
0
24
8
16
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
16
8
39
24
0
0
16
16
16
0
0
39
8
0
8
% P
% Gln:
0
8
0
0
24
0
0
8
24
0
0
8
0
0
0
% Q
% Arg:
8
8
0
0
0
0
16
8
0
0
31
8
8
8
0
% R
% Ser:
8
16
24
39
31
8
24
24
8
8
16
16
16
8
8
% S
% Thr:
24
0
0
0
8
8
0
0
8
8
0
16
0
8
0
% T
% Val:
0
8
8
8
0
16
8
0
0
8
8
0
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
16
8
0
16
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _